However, if the condition is acquired (not genetic), and a blood clot travels to the heart, brain or lungs . PDF Factor V Leiden - Blood Clots Treatment. successful pregnancy with factor v leiden Federici EH et al. In the European Prospective Cohort on Thrombophilia, the odds ratio (OR) for stillbirth (defined as pregnancy loss at > 28 weeks' gestation) among women with an inherited thrombophilia was 3.6 (95% confidence interval [CI] 1.4-9.4), whereas the risk of miscarriage before 28 weeks' gestation in this cohort was . successful pregnancy with factor v leiden . What are the Risk Factors - American Factor V Leiden Association 1,2 Factor V Leiden is common among whites, with a prevalence of up to 15% in healthy individuals and 17% to 56% (depending on patient selection) in thrombosis cohorts. 2008 - Was bed ridden with a stomach flu for about a week (while on birth control pills) and soon after my flu ended began experiencing severe back pain and fever. The type of Factor V Leiden where you have inherited 1 mutated Factor V Leiden gene and 1 normal Factor V gene. They're fine with it if someone only wants to do blood thinners around risky life events like your doctor suggested, but it isn't their recommendation. However, your doctor might suggest that you take extra precautions to prevent blood . Heterozygous Vs. Homozygous - Factor V Leiden: A Community Resource Blog The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). Clots in other areas of the body, such as the veins of major organs like the brain, liver and lungs, can be acutely life-threatening, and arterial clots can cause stroke and heart attack. The normal blood clotting process goes to work right away when you get a cut — platelets rush to the site to seal it, and a substance called fibrin — aided by factor V — helps the platelets to form a clot. Some clots do no damage and disappear on their own. Hille E.T. To investigate whether resistance to activated protein C (APC resistance) because of a mutation in the factor V gene (factor V Leiden) leads to a decrease in life expectancy, we analyzed overall . Westendorp R.G. Meijer K, Schulman S. Clinical features in 36 patients homozygous for the ARG 506->GLN factor V mutation. Factor V Leiden is an inherited disorder that makes blood more likely to clot. Mortality and Causes of Death in Families With the Factor V Leiden ... If you have the heterozygous form of factor V Leiden, the lifetime risk of developing a DVT is 10% or less, but may be higher if you have close family members who have had a DVT. Doctors generally prescribe blood-thinning medications to treat people who develop abnormal blood clots. Home - Factor v Leiden High risk of thrombosis recurrence in patients with homozygous and compound heterozygous factor V R506Q (Factor V Leiden) and prothrombin G20210A.